Biomarker Scientist
Posted 15/05/2024 by CK Group- Science, Clinical and Technical
Salary:
Hourly: From £20.03 PAYE or £27.27 Umbrella
Biomarker Scientist Role:
- Our client is recruiting for a high caliber scientist to join the team to support clinical transcriptomics as a Subject Matter Expert.
- The successful applicant will be responsible for planning and technical oversight of Biomarker Transcriptomics activities outsourced to CROs.
Your Background:
Candidates should have a BSc or higher academic qualification in a biological discipline with good theoretical understanding of the principals of molecular biology and transcriptomics (in particular RNA sequencing and RT-qPCR), and the application to biomarker analysis in clinical studies.
- Practical experience of the complete workflow for RNA sequencing experiments, from sample extraction, library preparation and quality control, sequencing runs, including troubleshooting.
- Practical experience in Molecular Biology methods, including RNA extraction from a variety of biofluids and tissue matrices, primer and probe design, quantitative PCR (real-time and/or ddPCR) and data analysis.
- Excellent organisation skills and attention to detail essential, alongside enthusiasm to strengthen existing workflows and reporting.
- Clear grasp of context of use (linking biomarker assay requirements to the usage of the data generated).
- Demonstrated ability to work flexibly in a dynamic environment to meet project needs and timelines with minimal supervision.
- Ability to work in a matrix team and communicate in a clear and timely manner with a wide range of internal and external stakeholders.
- Adaptable to changing project and organizational priorities, aligned with departmental needs.
Preferred - Experience of working in a pharmaceutical drug discovery and development environment.
- Experience of Protein analysis using O-LINK
- Experience working with Contract Research Organisations (CROs) to oversee method development, validation and/or sample analysis to agreed deadlines.
- Experience in tissue and biofluid collection, handling and storage in clinical settings.
- Experience of working with human tissue under the directives of the Human Tissue Act (HTA), and experience of working with samples and studies under GCP compliance.
- Practical experience in any of the following techniques would be an advantage: histology and immunohistochemistry, Immunoassay and ligand binding assays, Flow cytometry assays, LC-MS.
Our client is a is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.
Location:
This role is based at our clients site in Slough.
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference (phone number removed) in all correspondence.
Please note:
This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.
- Type:
- Contract
- Start Date:
- ASAP
- Contract Length:
- 12 months
- Contact Name:
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- Telephone:
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- Job Reference:
- V-101277-1
- Job ID:
- 221657484
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